Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware 19716; Department of Physics and Astronomy, University of Delaware, Newark, Delaware 19716. Electronic address: [email protected].

Micellar Morphology of Polysorbate 20 and 80 and Their Ester Fractions in Solution via Small-Angle Neutron Scattering.

Published in Journal of Pharmaceutical Sciences

Surfactants are commonly used in therapeutic protein formulations in biopharmaceuticals to impart protein stability; however, their solution morphology and the role of the individual components in these structurally heterogeneous commercial grade surfactants at physiologically and pharmaceutically relevant temperatures have not been investigated sy...