Department of Cell Biology and

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Chemical inhibition of FBXO7 reduces inflammation and confers neuroprotection by stabilizing the mitochondrial kinase PI...

Liu, Yuan Lear, Travis B. Verma, Manish Wang, Kent Z.Q. Otero, Anthony McKelvey, Alison C. Dunn, Sarah R. Steer, Erin Bateman, Nicholas W. Wu, Christine ...

Published in JCI Insight

E3 ligase component Fbxo7 targets Pink1 for cellular disposal, and an Fbxo7-targeting compoiund confers neuroprotection in multiple models.