Community Health Sciences Department, College of Applied Medic...

The present study aims to compare and evaluate radiographic and clinical parameters along with salivary proinflammatory cytokine profiles IL-1 - and IL-6 in the obese with peri implantitis Obese and non-obese participants in the present study were 80 The nonobese and obese participants were scrutinized based on inclusion and exclusion criteria All participants both obese and non-obese were subjected to full mouth mechanical debridement MD A single session of Photodynamic therapy PDT was provided to all obese participants Clinical peri implant parameters peri implant plaque index PIPI Peri-implant bleeding on probing PIBoP peri implant probing depth PIPD were assessed at baseline three months and six months Marginal bone loss MBL was also assessed Enzyme-linked immunosorbent assay ELISA was used to check the levels of IL-1 - and IL-6 in unstimulated whole saliva samples All the parameters were assessed using the Kruskal Wallis test and analysis of variance ANOVA Overall characteristics were assessed using descriptive statistics SPSS software was used for statistical analysis Clinical baseline periodontal parameters PIPI PIBoP PIPD and MBL in non-obese participants were significantly lower compared to group I obese participants at baseline p 0 05 At 3 months follow-up PDT adjunct to MD in group 1 obese participants PIPI and PIPD were significantly lower compared to MD alone in non-obese participants PIP1 and PIPD At 6 months follow up non-obese participants with peri implantitis treated with MD demonstrated PIPI and PIPD significantly lower compared to obese participants treated with PDT adjunct to MD CONCLUSION PDT adjunctive to MD enhanced periodontal parameters i e peri implant probing depth peri implant plaque index and peri implant bleeding on probing in obese with peri implantitis Moreover obese individuals with peri implantitis demonstrated high levels of proinflammatory cytokines IL-1 and IL-6 than control Copyright 2022 Published by Elsevier B V

Community Health Sciences Department, College of Applied Medical Sciences, King Saud University, P.O.Box 10219, Riyadh 11433, Saudi Arabia. Electronic address: [email protected].

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Assessment of clinical and radiographic peri‑implant parameters in the obese and non-obese, along with destructive pro-i...