Columbia University in the City of New York
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Publications Show all
Applying medicinal chemistry strategies to understand odorant discrimination
Published in Nature Communications
Associating an odorant's chemical structure with its percept is a long-standing challenge. One hindrance may come from the adoption of the organic chemistry scheme of molecular description and classification. Chemists classify molecules according to characteristics that are useful in synthesis or isolation, but which may be of little importance to ...
Functional odor classification through a medicinal chemistry approach
Published in Science Advances
Crucial for any hypothesis about odor coding is the classification and prediction of sensory qualities in chemical compounds. The relationship between perceptual quality and molecular structure has occupied olfactory scientists throughout the 20th century, but details of the mechanism remain elusive. Odor molecules are typically organic compounds o...
