College of Nursing, University of Toledo, Toledo, OH, USA.

Chronic periodontitis can affect the levels of potential oral cancer salivary mRNA biomarkers.

Published in Journal of Periodontal Research

Salivary S100P mRNA could be a reliable biomarker for OSCC detection, regardless of the presence of chronic periodontitis. The presence of chronic periodontitis could significantly affect the levels of the other six mRNAs, and negatively influence reliability for using them as biomarkers for oral cancer detection.