College of Applied Sciences, University of Bahri, Sudan

This study was carried out in Khartoum state-Sudan during March this plant was collected from Al-Dubibat area locality of al-goze South Kordofan State western Sudan The dried root of Hydnora abyssinicia was extracted successively with petroleum ether chloroform and methanol The phytochemical screening carried out for different plant roots extracts and showed that it contain high amount of alkaloids in all extract and moderate amount of flavonoids in chloroform methanol extracts and moderate amount of tannins sterol and triterpenes also moderate amount of cardiac glycoside and high amount of saponins The antimicrobial activity of extracts were evaluated against four standard bacteria Gram positive Bacillus subtilis Staphylococcus aureus and Gram negative Escherichia coli Pseudomonas aeruginosa in addition of one standard fungi Candida albicans The result of antimicrobial tests indicated that the methanolic extract inhibited the growth of all microorganisms and most extracts showed same degree of antimi-crobial activity The result provide promising baseline information for the potential use of these crude extracts in the treatment of bacterial and fungal infections Sudan is the largest country in Africa it has a wide diversity climate which is responsible for its varied vegetation and very rich flora Many species of plants grow abundantly in the Sudan and other African countries and are used by the village populations for treatment of various disorders 1 2 The Sudanese folkloric medicine represents a unique blend of indigenous cultures with Egyptian Indian Arabian East and West African cultures 3 17 In Sudan plants are the main medicinal source to treat infectious diseases 4 in many developing countries like Sudan the medicinal plants have played an important role in the treatment of diseases especially in rural areas The medicinal and aromatic plants contain a number of chemical constituents such as alkaloids flavo-noids tannins saponins glycosides and others isolated and used as an important source of indispensable drugs 5 6 15 State that medicinal plants are known by their required clinical effects on the abnormal living tissues or organs while toxic ones are known by their ability to cause a non-required physiological deviation in animals bodies the traditional medicinal plants are increase in both developing and industrialized countries 7 8 16 17 reported that both literate and illiterate people still use local plants as drugs in many conditions 9 Many secondary metabolites of plant are commercially important and find use in a number of pharmaceutical compounds However a sustained supply of the source material often becomes difficult due to the factors like environmental changes cultural practices diverse geographical distribution labor cost and selection of the superior plant stock and over exploitation by pharmaceutical industry 10 The species Hydnora abyssinicia belong to family Hydnoraceae locally known as tartous was chosen because it s using traditionally in treatment of many abdominal disease Phytochemical activities were investigated to detect the effects of antimicrobial

College of Applied Sciences, University of Bahri, Sudan

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Phytochemical Screening and Antimicrobial Activity of Hydnora abyssinicia Root Extract