CNRS (ICSN), Gif‐Sur‐Yvette, France

Production of biologically active forms of recombinant hepcidin, the iron-regulatory hormone.

Published in The FEBS Journal

Hepcidin is a liver produced cysteine-rich peptide hormone that acts as the central regulator of body iron metabolism. Hepcidin is synthesized under the form of a precursor, prohepcidin, which is processed to produce the biologically active mature 25 amino acid peptide. This peptide is secreted and acts by controlling the concentration of the membr...