Centre for Cytochrome P450 Biodiversity, Institute of Life Science, Swansea University Medical School, Swansea, UK.

In vivo emergence of high-level resistance during treatment reveals the first identified mechanism of amphotericin B res...

Published in Clinical Microbiology and Infection

Candida auris has emerged as a health-care-associated and multidrug-resistant fungal pathogen of great clinical concern. As many as 50% of C. auris clinical isolates are reported to be resistant to amphotericin B, but no mechanisms contributing to this resistance have been identified. Here we describe a clinical case in which high-level amphoterici...