Centre for Colloid and Surface Science – C.S.G.I. Operative Unit of Bari, c/o Chemistry Department, University “Aldo Moro”, Bari, Italy

A fluorescence study of the loading and time stability of doxorubicin in sodium cholate/PEO-PPO-PEO triblock copolymer m...

Published in Journal of Colloid and Interface Science

Hypothesis Doxorubicin hydrochloride (DX) is one of the most powerful anticancer agents though its clinical use is impaired by severe undesired side effects. DX encapsulation in nanocarrier systems has been introduced as a mean to reduce its toxicity. Micelles of the nonionic triblock copolymers of poly(ethylene oxide) (PEO) and poly(propylene oxi...