Center for Molecular and Engineering Thermodynamics, Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware 19716. Electronic address: [email protected].

Data-Driven Development of Predictive Models for Sustained Drug Release.

Published in Journal of Pharmaceutical Sciences

Mathematical modeling of drug release can aid in the design and development of sustained delivery systems, but the parameter estimation of such models is challenging owing to the nonlinear mathematical structure and complexity and interdependency of the physical processes considered. Highly parameterized models often lead to overfitting, strong par...