AP-HP, Pharmacology Department, Saint-Louis Hospital.

Development and Validation of a Simultaneous Quantification Method of Ruxolitinib, Vismodegib, Olaparib, and Pazopanib i...

Published in Therapeutic drug monitoring

A simple, rapid, and sensitive liquid chromatography coupled with tandem mass spectrometry method has been developed and validated for the quantification of ruxolitinib, olaparib, vismodegib, and pazopanib in human plasma. After a simple protein precipitation of plasma samples, the chromatographic separation was performed using an ultraperformance ...