AET Laboratories, Analytical Research and Development, Gaddapotharam, Hyderabad 502319, Telangana, India

QbD-Based UPLC Method for Quantification of Brexpiprazole in Presence of Impurities and Application to In Vitro Dissolut...

Published in Journal of Chromatographic Science

Quality-by-design-based UPLC method was developed for chromatographic separation to quantify the antischizophrenic drug brexpiprazole in the presence of impurities. Research findings from pH-scouting studies were used as control variables which influence the chromatographic separation. The peak tailing and resolution are the response variables and ...