1 Department of Neurosurgery, the First Affiliated Hospital of Xi'an Jiaotong, University College of Medicine, Xi'an, China.

miR-139 Functions as An Antioncomir to Repress Glioma Progression Through Targeting IGF-1 R, AMY-1, and PGC-1β.

Published in Technology in Cancer Research & Treatment

Gliomas are the most common primary malignant brain tumor with poor prognosis, characterized by a highly heterogeneous cell population, extensive proliferation, and migration. A lot of molecular mechanisms regulate gliomas development and invasion, including abnormal expression of oncogenes and variation of epigenetic modification. MicroRNAs could ...