Serruya, Suzanne J Gómez Ponce de León, Rodolfo Bahamondes, Maria V De Mucio, Bremen Costa, Maria L Durán, Pablo Díaz-Rosello, José L Kim, Caron Lavelanet, Antonella F Artigas, Ana
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Published in
Global health action
Maternal mortality is unacceptably high in our region. In 2015, the Latin American Center for Perinatology and Women´s Reproductive Health (CLAP) created a regional network of institutions including 16 countries, committed to improving epidemiological surveillance and healthcare of women in a situation of abortion or near miss event, using a common...
Londoño Agudelo, Esteban García Fariñas, Anaí Pérez Ospina, Viviana Taborda Pérez, Cecilia Villacrés Landeta, Tatiana Battaglioli, Tullia Gómez Arias, Rubén Van der Stuyft, Patrick
Published in
Global health action
Background Hypertension requires life-long medical care, which may cause economic burden and even lead to catastrophic health expenditure. Objective To estimate the extent of out-of-pocket expenditure for hypertension care at a population level and its impact on households' budgets in a low-income urban setting in Colombia. Methods We conducted a c...
Oni, Tolu Micklesfield, Lisa K Wadende, Pamela Obonyo, Charles O Woodcock, James Mogo, Ebele R I Odunitan-Wayas, Feyisayo A Assah, Felix Tatah, Lambed Foley, Louise
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Published in
Global health action
At the time of writing, it is unclear how the COVID-19 pandemic will play out in rapidly urbanising regions of the world. In these regions, the realities of large overcrowded informal settlements, a high burden of infectious and non-communicable diseases, as well as malnutrition and precarity of livelihoods, have raised added concerns about the pot...
Tchakarska, Guergana Sola, Brigitte
The cell cycle is tightly regulated by cyclins and their catalytic moieties, the cyclin-dependent kinases (CDKs). Cyclin D1, in association with CDK4/6, acts as a mitogenic sensor and integrates extracellular mitogenic signals and cell cycle progression. When deregulated (overexpressed, accumulated, inappropriately located), cyclin D1 becomes an on...
Whittaker, Gary R. Millet, Jean K.
Published in
MERS Coronavirus
The coronavirus spike envelope glycoprotein is an essential viral component that mediates virus entry events. Biochemical assessment of the spike protein is critical for understanding structure–function relationships and the roles of the protein in the viral life cycle. Coronavirus spike proteins are typically proteolytically processed and activate...
Gómez, Juan Albaiceta, Guillermo M García-Clemente, Marta López-Larrea, Carlos Amado-Rodríguez, Laura Lopez-Alonso, Inés Hermida, Tamara Enriquez, Ana I Herrero, Pablo Melón, Santiago
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Published in
Gene
The Angiotensin system is implicated in the pathogenesis of COVID-19. First, ACE2 is the cellular receptor for SARS-CoV-2, and expression of the ACE2 gene could regulate the individuaĺs susceptibility to infection. In addition, the balance between ACE1 and ACE2 activity has been implicated in the pathogenesis of respiratory diseases and could play ...
Jouan, Youenn Guillon, Antoine Gonzalez, Loïc Perez, Yonatan Boisseau, Chloé Ehrmann, Stephan Ferreira, Marion Daix, Thomas Jeannet, Robin François, Bruno
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Published in
The Journal of experimental medicine
COVID-19 includes lung infection ranging from mild pneumonia to life-threatening acute respiratory distress syndrome (ARDS). Dysregulated host immune response in the lung is a key feature in ARDS pathophysiology. However, cellular actors involved in COVID-19-driven ARDS are poorly understood. Here, in blood and airways of severe COVID-19 patients, ...
Nazareno, Jennifer Zhang, Wenhan Silver, Benjamin Dosa, David Gozalo, Pedro Thomas, Kali
Published in
Medical care research and review : MCRR
Home health agencies (HHAs) are one of the most commonly used third-party providers in the assisted living (AL) setting. One way ALs may be potentially able to meet the needs of their residents despite increased impairment is through supplementing the services offered with those delivered by HHAs. We explore the growth in the delivery of HHA servic...
Giner Perot, Julie Jarzebowski, Witold Lafuente-Lafuente, Carmelo Crozet, Cyril Belmin, Joël
Published in
BMC Geriatrics
BackgroundHealth professionals working with older persons are not sufficiently aware of the sensory and functional difficulties experienced by older patients. Innovative educational activities, such as the aging-simulation experience, can facilitate this awareness. This study describes the effects of an aging-simulation experience on health profess...
Corroenne, Romain El Hachem, Hady Verhaeghe, Caroline Legendre, Guillaume Dreux, Cecile Jeanneteau, Pauline Descamps, Philippe May-Panloup, Pascale Bouet, Pierre-Emmanuel
Published in
Scientific Reports
The objective was to compare the endometrial thickness (ET) in a frozen embryo transfer (FET) cycle between transdermal and vaginal estrogen. Our secondary objectives were to compare the patient satisfaction and the pregnancy outcomes. Prospective monocentric cohort study between 01/2017 and 12/2017 at a single institution. Choice of administration...
