Chen, Chun-Hsien Wang, Yu-Jen Huang, Jian-Ming Huang, Fu-Chin Lin, Wei-Chen
Published in
Antimicrobial agents and chemotherapy
Acanthamoeba spp. are free-living protozoan that cause a serious human eye disease called Acanthamoeba keratitis (AK). Several new and effective medical therapy for AK patients remains highly debated and therefore, CHG is still considered one of the first lines of treatment for AK patients. We hypothesized that ocular microenvironmental factors are...
Hopkins, Brian J Prokesch, Bonnie C
Published in
Antimicrobial agents and chemotherapy
In December 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first detected in Wuhan, China and found to cause acute respiratory symptoms and pneumonia.1…. Copyright © 2021 American Society for Microbiology.
Tomita, Yuriko Takeda, Makoto Matsuyama, Shutoku
Published in
Antimicrobial agents and chemotherapy
Favipiravir (T-705, commercial name Avigan), a drug developed to treat influenza virus infection, has been used in some countries as an oral treatment for COVID-19; however, its clinical efficacy in this context is controversial.…. Copyright © 2021 Tomita et al.
谢, 卓瑄 陈, 保义
Published in
Chinese Physics C
We treat heavy quark as an open quantum system in a hot medium and rederive the stochastic Schrödinger equation (SSE) from the full Schrödinger equation for both heavy quarks and the medium. We apply the SSE to the dynamical evolutions of a heavy quark (as a system) in the static hot medium (as an environment). Heavy quarks interact with the medium...
Hulley, Joanne Wager, Khai Gomersall, Tim Bailey, Louis Kirkman, Gill Gibbs, Graham Jones, Adele D
Published in
Journal of interpersonal violence
Intimate partner violence causes significant, long-lasting harm to almost one-third (27%) of the world's population of women. Even when women leave abusive relationships, some men continue to exercise control over their ex-partners through psychological control, threats, violence, stalking, and other forms of harassment. In this qualitative study, ...
Hong, Yu-Ping Chen, Ying-Tsong Wang, You-Wun Chen, Bo-Han Teng, Ru-Hsiou Chen, Yi-Syong Chiou, Chien-Shun
Published in
Antimicrobial agents and chemotherapy
We identified an erm42-carrying integrative and conjugative element, ICE_erm42, in 26.4% of multidrug-resistant Salmonella enterica serovar Albany isolates recovered from human salmonellosis between 2014 and 2019 in Taiwan. ICE_erm42-carrying strains displayed high-level resistance to azithromycin and the element could move into the phylogeneticall...
Andrade-Neto, Valter V Rebello, Karina M Pereira, Thais M Torres-Santos, Eduardo Caio
Published in
Antimicrobial agents and chemotherapy
Drug combination therapy is an interesting approach to increase the success of drug repurposing for neglected diseases. Thus, the objective of this work was to evaluate binary and ternary therapies composed of itraconazole, ezetimibe and miltefosine for the treatment of visceral leishmaniasis. Intracellular Leishmania infantum amastigotes were incu...
Bruggemans, Anne Vansant, Gerlinde Balakrishnan, Mini Mitchell, Michael L Cai, Ruby Christ, Frauke Debyser, Zeger
Published in
Antimicrobial agents and chemotherapy
The ability of HIV to integrate into the host genome and establish latent reservoirs is the main hurdle preventing an HIV cure. LEDGINs are small-molecule integrase inhibitors that target the binding pocket of LEDGF/p75, a cellular cofactor that substantially contributes to HIV integration site selection. They are potent antivirals that inhibit HIV...
Ruiz-Ruigómez, María Fernández-Ruiz, Mario Silva, José Tiago Vidal, Elisa Origüen, Julia Calvo-Cano, Antonia Luna-Huerta, Enrique Merino, Esperanza Hernández, Domingo Jironda-Gallegos, Cristina
...
Published in
Antimicrobial agents and chemotherapy
Current guidelines recommend against systematic screening or treating asymptomatic bacteriuria (AB) among kidney transplant (KT) recipients, although the evidence regarding episodes occurring early after transplantation or in the presence of anatomical abnormalities is inconclusive. Oral fosfomycin may constitute a good option for the treatment of ...
Rezzoug, Inès Emeraud, Cécile Sauvadet, Aimie Cotellon, Garance Naas, Thierry Dortet, Laurent
Published in
Antimicrobial agents and chemotherapy
The MAST® Carba PAcE test is a colorimetric test used to detect carbapenemase-producing Gram-negative bacilli from cultured colonies. The performances of this test were compared to β-CARBA™, Carba NP test and RAPIDEC® CARBA NP tests using a collection of 280 characterized isolates. Sensitivity and specificity of the MAST® Carba PAcE test were 79.8%...
